ACR 2022 | COVID-19 vaccination advocated for pregnant women with RMDs

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medwireNews: Vaccination against COVID-19 should be actively promoted for women with rheumatic and musculoskeletal diseases (RMDs) who are pregnant or planning a pregnancy, researchers say.

Their findings, presented on a poster at ACR Convergence 2022 in Philadelphia, Pennsylvania, USA, showed a higher rate of preterm birth in 47 unvaccinated or partially vaccinated (one dose) women with RMD who developed COVID-19 during their pregnancy than 26 comparable women. women who were fully vaccinated (two or more doses), by 29.5% versus 18.2%. However, the difference between the groups did not reach statistical significance.

The most common RMDs were systemic lupus erythematosus (23%) and rheumatoid arthritis (21.9%) and the majority (70%) of patients were in remission when diagnosed with COVID-19.

At the time of data extraction, there were 55 completed pregnancies, of which 50 were live births. The most common neonatal complication was low birth weight (

Most women were not vaccinated when they were diagnosed with COVID-19, while 4% were partially vaccinated and 36% were fully vaccinated.

Hospitalization was necessary for 21% of women regardless of vaccination status, but only 16% required COVID-19-specific medication.

“This would mean that the severity of COVID-19 was comparable between vaccinated and partially vaccinated or unvaccinated women,” said Sinead Maguire (St James’ Hospital, Dublin, Ireland) in a press release. “This was an unexpected result, given the differences in obstetric and neonatal outcomes.”

medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group

November 15, 2022: The coronavirus pandemic affects all healthcare professionals around the world. During this difficult time, Medicine Matters’ focus is on disseminating the latest data to support you in your research and clinical practice, based on the scientific literature. We will update the information we provide on the site as the data is published. However, please refer to your own professional and government guidelines for the most current guidelines in your own country.

ACR convergence 2022; Philadelphia, Pennsylvania, US: November 10-14

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