Opioid use disorder (OUD) is common and associated with inadequate treatment and deaths due to opioid overdose. Therefore all clinicians, not just those specializing in addiction medicine, should be able to effectively engage with patients with OUD about preventing overdose. Overdose deaths persist in the US, with 81 083 fatal overdoses in 2023, primarily related to polysubstance use and novel adulterants in the drug supply.1 Drug overdose affects people of all ages in all US states and disproportionately affects racial and ethnic minority groups. A study using Medicaid data to assess health service patterns before opioid-related death found that 60% of decedents had 1 or more outpatient health care visits within 30 days of death, underscoring missed opportunities for clinicians to provide overdose prevention education.²